Whole genome sequencing of an unusual serotype of Shiga toxin-producing Escherichia coli.

ABSTRACT

Shiga toxin-producing Escherichia coli serotype O117K1H7 is a cause of persistent diarrhea in travelers to tropical locations. Whole genome sequencing identified genetic mechanisms involved in the pathoadaptive phenotype. Sequencing also identified toxin and putative adherence genes flanked by sequences indicating horizontal gene transfer from Shigella dysenteriae and Salmonella spp., respectively.