Whole brain perfusion measurements using arterial spin labeling with multiband acquisition.
Magn Reson Med
; 70(6): 1653-61, 2013 Dec.
Article
em En
| MEDLINE
| ID: mdl-23878098
ABSTRACT
PURPOSE:
The multiband (MB) excitation and reconstruction technique was both developed and evaluated for accelerated data acquisition of arterial spin labeling (ASL) to cover whole brain perfusion maps. THEORY ANDMETHODS:
MB excitation was incorporated into a pulsed ASL (PASL) technique and compared with conventional single-band excitation PASL from healthy subjects, using a 32-channel head receiver coil at 3 T. The MB de-aliasing performance and effectiveness in perfusion measurement were measured with varying MB acceleration factors and gaps between MB excitations.RESULTS:
The MB PASL perfusion maps were in good agreement with the conventional single-band PASL maps at matched slices. The imaging coverage could be effectively extended with the MB technique by a factor up to 5. A gap as small as 3 cm between MB excitations resulted in a comparable ASL signal loss and temporal-signal-to-noise ratio with single-band PASL.CONCLUSION:
The MB ASL technique is an effective method to evaluate whole brain perfusion because it minimizes the temporal spread of labeled spins across slices, resulting in more accurate perfusion measurements.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Algoritmos
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Interpretação de Imagem Assistida por Computador
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Artérias Cerebrais
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Circulação Cerebrovascular
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Angiografia por Ressonância Magnética
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Female
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Humans
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Middle aged
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article