Strain-induced differentiation of fetal type II epithelial cells is mediated via the integrin &#945;6ß1-ADAM17/tumor necrosis factor-&#945;-converting enzyme (TACE) signaling pathway.

Wang, Yulian; Huang, Zheping; Nayak, Pritha S; Matthews, Benjamin D; Warburton, David; Shi, Wei; Sanchez-Esteban, Juan

Strain-induced differentiation of fetal type II epithelial cells is mediated via the integrin α6ß1-ADAM17/tumor necrosis factor-α-converting enzyme (TACE) signaling pathway.

Wang, Yulian; Huang, Zheping; Nayak, Pritha S; Matthews, Benjamin D; Warburton, David; Shi, Wei; Sanchez-Esteban, Juan.

Afiliação

Wang Y; From the Department of Pediatrics, Women & Infants Hospital of Rhode Island and the Warren Alpert Medical School, Brown University, Providence, Rhode Island 02905.
Huang Z; From the Department of Pediatrics, Women & Infants Hospital of Rhode Island and the Warren Alpert Medical School, Brown University, Providence, Rhode Island 02905.
Nayak PS; From the Department of Pediatrics, Women & Infants Hospital of Rhode Island and the Warren Alpert Medical School, Brown University, Providence, Rhode Island 02905.
Matthews BD; the Vascular Biology Program, Departments of Medicine, Pathology, and Surgery, Harvard Medical School and Boston Children's Hospital, Boston, Massachusetts 02115, and.
Warburton D; the Developmental Biology and Regenerative Medicine Program, Saban Research Institute of Children's Hospital Los Angeles, University of Southern California, Los Angeles, California 90027.
Shi W; the Developmental Biology and Regenerative Medicine Program, Saban Research Institute of Children's Hospital Los Angeles, University of Southern California, Los Angeles, California 90027.
Sanchez-Esteban J; From the Department of Pediatrics, Women & Infants Hospital of Rhode Island and the Warren Alpert Medical School, Brown University, Providence, Rhode Island 02905,. Electronic address: jsanchezesteban@wihri.org.

J Biol Chem ; 288(35): 25646-25657, 2013 Aug 30.

Article em En | MEDLINE | ID: mdl-23888051

Assuntos

Proteínas ADAM/metabolismo; Diferenciação Celular/fisiologia; Células Epiteliais/metabolismo; Integrina alfa6beta1/metabolismo; Pulmão/embriologia; Mucosa Respiratória/embriologia; Transdução de Sinais/fisiologia; Proteínas ADAM/genética; Proteína ADAM17; Animais; Células Epiteliais/citologia; Fator de Crescimento Semelhante a EGF de Ligação à Heparina; Integrina alfa6beta1/genética; Peptídeos e Proteínas de Sinalização Intercelular/genética; Peptídeos e Proteínas de Sinalização Intercelular/metabolismo; Pulmão/citologia; Camundongos; Camundongos Knockout; Ligação Proteica; Mucosa Respiratória/citologia; Estresse Fisiológico/fisiologia; Fator de Crescimento Transformador alfa/genética; Fator de Crescimento Transformador alfa/metabolismo

Palavras-chave

ADAM ADAMTS; Cell Differentiation; Cell Signaling; Cell Surface Receptor; Growth Factors; Integrins; Lung; Mechanotransduction

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Diferenciação Celular / Mucosa Respiratória / Integrina alfa6beta1 / Células Epiteliais / Proteínas ADAM / Pulmão Limite: Animals Idioma: En Ano de publicação: 2013 Tipo de documento: Article

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