Endothelial microparticles: sophisticated vesicles modulating vascular function.
Vasc Med
; 18(4): 204-14, 2013 Aug.
Article
em En
| MEDLINE
| ID: mdl-23892447
ABSTRACT
Endothelial microparticles (EMPs) belong to a family of extracellular vesicles that are dynamic, mobile, biological effectors capable of mediating vascular physiology and function. The release of EMPs can impart autocrine and paracrine effects on target cells through surface interaction, cellular fusion, and, possibly, the delivery of intra-vesicular cargo. A greater understanding of the formation, composition, and function of EMPs will broaden our understanding of endothelial communication and may expose new pathways amenable for therapeutic manipulation.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças Vasculares
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Endotélio Vascular
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Transdução de Sinais
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Comunicação Celular
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Células Endoteliais
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Micropartículas Derivadas de Células
Limite:
Animals
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Humans
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article