Potential and limitations of diffusion MRI tractography for the study of language.
Brain Lang
; 131: 65-73, 2014 Apr.
Article
em En
| MEDLINE
| ID: mdl-23910928
ABSTRACT
Diffusion magnetic resonance imaging (MRI) is a tremendously promising tool for imaging tissue microstructure, and for inferring large scale structural connectivity in vivo. However, the sensitivity of the technique is highly dependent on methodological details. Acquisition parameters, pre-processing steps, reconstruction models, and statistical analysis all affect the final sensitivity, specificity, and accuracy of a study. In the case of fiber pathway reconstruction in the central nervous system, termed tractography, false positive and false negative results abound, and interpretation of results must take into account the potential shortcomings of the techniques used. This article will review the strengths and limitations of different types of diffusion MRI tractography analysis, and highlight what one can realistically hope to learn from such imaging studies of the human brain.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Encéfalo
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Imagem de Difusão por Ressonância Magnética
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Imagem de Tensor de Difusão
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Idioma
Tipo de estudo:
Prognostic_studies
Limite:
Animals
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Humans
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article