Signaling pathways regulating ectodermal cell fate choices.
Exp Cell Res
; 321(1): 11-6, 2014 Feb 01.
Article
em En
| MEDLINE
| ID: mdl-23939346
ABSTRACT
Although embryonic patterning and early development of the nervous system have been studied for decades, our understanding of how signals instruct ectodermal derivatives to acquire specific identities has only recently started to form a coherent picture. In this mini-review, we summarize recent findings and models of how a handful of well-known secreted signals influence progenitor cells in successive binary decisions to adopt various cell type specific differentiation programs.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Células-Tronco
/
Transdução de Sinais
/
Diferenciação Celular
/
Linhagem da Célula
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Ectoderma
Tipo de estudo:
Prognostic_studies
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article