Radiobiological characterization of head and neck and sarcoma cells derived from patients prior to radiotherapy.
Int J Radiat Oncol Biol Phys
; 19(2): 313-9, 1990 Aug.
Article
em En
| MEDLINE
| ID: mdl-2394610
ABSTRACT
The radiobiological parameters of 33 tumor cell lines were studied in biopsy samples obtained from patients prior to radiotherapy. Epithelial tumor cells derived from head and neck cancer patients were more radioresistant than tumor cell lines derived from patients with sarcoma regardless of method of analysis. The presence of radioresistant tumor cell lines was associated with local failure in some patients. However, the presence of radiosensitive tumor cells did not necessarily predict local control. Our data suggest radiocurability is complex and inherent radiobiological parameters of tumor cells may be only one factor in radiotherapy outcome.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Tolerância a Radiação
/
Sarcoma
/
Carcinoma de Células Escamosas
/
Sobrevivência Celular
/
Neoplasias de Cabeça e Pescoço
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
1990
Tipo de documento:
Article