Comet assay measures of DNA damage are predictive of bladder cancer cell treatment sensitivity in vitro and outcome in vivo.

Bowman, Karen J; Al-Moneef, Manar M; Sherwood, Benedict T; Colquhoun, Alexandra J; Goddard, Jonathan C; Griffiths, T R Leyshon; Payne, David; Singh, Sadmeet; Butterworth, Paul C; Khan, Masood A; Summerton, Duncan J; Steward, William P; McKelvey-Martin, Valerie J; McKeown, Stephanie R; Kockelbergh, Roger C; Mellon, J Kilian; Symonds, R Paul; Jones, George D D

Bowman, Karen J; Al-Moneef, Manar M; Sherwood, Benedict T; Colquhoun, Alexandra J; Goddard, Jonathan C; Griffiths, T R Leyshon; Payne, David; Singh, Sadmeet; Butterworth, Paul C; Khan, Masood A; Summerton, Duncan J; Steward, William P; McKelvey-Martin, Valerie J; McKeown, Stephanie R; Kockelbergh, Roger C; Mellon, J Kilian; Symonds, R Paul; Jones, George D D.

Afiliação

Bowman KJ; Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester, United Kingdom.

Int J Cancer ; 134(5): 1102-11, 2014 Mar 01.

Article em En | MEDLINE | ID: mdl-23959905

Assuntos

Ensaio Cometa/métodos; Dano ao DNA; Neoplasias da Bexiga Urinária/tratamento farmacológico; Linhagem Celular Tumoral; Cisplatino/farmacologia; Humanos; Mitomicina/farmacologia; Resultado do Tratamento; Neoplasias da Bexiga Urinária/genética

Palavras-chave

Comet assay; DNA damage; bladder cancer; cell sensitivity; recurrence; treatment

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Bexiga Urinária / Dano ao DNA / Ensaio Cometa Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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