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A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip.
Evangelou, Evangelos; Kerkhof, Hanneke J; Styrkarsdottir, Unnur; Ntzani, Evangelia E; Bos, Steffan D; Esko, Tonu; Evans, Daniel S; Metrustry, Sarah; Panoutsopoulou, Kalliope; Ramos, Yolande F M; Thorleifsson, Gudmar; Tsilidis, Konstantinos K; Arden, Nigel; Aslam, Nadim; Bellamy, Nicholas; Birrell, Fraser; Blanco, Francisco J; Carr, Andrew; Chapman, Kay; Day-Williams, Aaron G; Deloukas, Panos; Doherty, Michael; Engström, Gunnar; Helgadottir, Hafdis T; Hofman, Albert; Ingvarsson, Thorvaldur; Jonsson, Helgi; Keis, Aime; Keurentjes, J Christiaan; Kloppenburg, Margreet; Lind, Penelope A; McCaskie, Andrew; Martin, Nicholas G; Milani, Lili; Montgomery, Grant W; Nelissen, Rob G H H; Nevitt, Michael C; Nilsson, Peter M; Ollier, William Er; Parimi, Neeta; Rai, Ashok; Ralston, Stuart H; Reed, Mike R; Riancho, Jose A; Rivadeneira, Fernando; Rodriguez-Fontenla, Cristina; Southam, Lorraine; Thorsteinsdottir, Unnur; Tsezou, Aspasia; Wallis, Gillian A.
Afiliação
  • Evangelou E; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece Department of Twin Research & Genetic Epidemiology, King's College London, London, UK.
  • Kerkhof HJ; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Styrkarsdottir U; Department of Population Genetics, deCODE Genetics, Reykjavik, Iceland.
  • Ntzani EE; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece.
  • Bos SD; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands Netherlands Consortium for Healthy Ageing, The Netherlands.
  • Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.
  • Evans DS; California Pacific Medical Center Research Institute, San Francisco, USA.
  • Metrustry S; Department of Twin Research & Genetic Epidemiology, King's College London, London, UK.
  • Panoutsopoulou K; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Ramos YF; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Thorleifsson G; Department of Population Genetics, deCODE Genetics, Reykjavik, Iceland.
  • Tsilidis KK; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece.
  • Arden N; NIHR Biomedical Research Unit and ARUK Centre of excellence for Sport, Exercise and Osteoarthritis, University of Oxford, Oxford, UK MRC Epidemiology Resource Centre, University of Southampton, Southampton, UK.
  • Aslam N; Worcestershire Royal Hospital, Worcestershire Acute Hospitals NHS Trust, Worcester, UK.
  • Bellamy N; Centre of National Research on Disability and Rehabilitation Medicine, The University of Queensland, Brisbane, Australia.
  • Birrell F; Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK Wansbeck General Hospital, Northumbria Healthcare NHS Foundation Trust, Ashington, UK.
  • Blanco FJ; Rheumatology Division, Instituto de Investigación Biomédica-Hospital Universitario A Coruña, A Corunna, Spain.
  • Carr A; NIHR Biomedical Research Unit and ARUK Centre of excellence for Sport, Exercise and Osteoarthritis, University of Oxford, Oxford, UK.
  • Chapman K; NIHR Biomedical Research Unit and ARUK Centre of excellence for Sport, Exercise and Osteoarthritis, University of Oxford, Oxford, UK.
  • Day-Williams AG; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Deloukas P; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Doherty M; Department of Academic Rheumatology, University of Nottingham, Nottingham, UK.
  • Engström G; Department of Clinical Sciences Malmo, Lund University, Malmo, Sweden.
  • Helgadottir HT; Department of Population Genetics, deCODE Genetics, Reykjavik, Iceland.
  • Hofman A; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Ingvarsson T; Department of Orthopedic Surgery, Akureyri Hospital, Akureyri, Iceland School of Health Sciences, University of Akureyri, Akureyri, Iceland.
  • Jonsson H; Department of Medicine, The National University Hospital of Iceland, Reykjavik, Iceland Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
  • Keis A; Department of Public Health, University of Tartu, Tartu, Estonia Orthopedic Surgeons, Elva Hospital, Elva, Estonia.
  • Keurentjes JC; Department of Orthopedics, Leiden University Medical Center, Leiden, The Netherlands.
  • Kloppenburg M; Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.
  • Lind PA; Department of Quantitative Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • McCaskie A; Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
  • Martin NG; Department of Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia.
  • Montgomery GW; Department of Molecular Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • Nelissen RG; Department of Orthopedics, Leiden University Medical Center, Leiden, The Netherlands.
  • Nevitt MC; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, USA.
  • Nilsson PM; Department of Clinical Sciences Malmo, Lund University, Malmo, Sweden.
  • Ollier WE; Centre for Integrated Genomic Medical Research, University of Manchester, Manchester, UK.
  • Parimi N; California Pacific Medical Center Research Institute, San Francisco, USA.
  • Rai A; Worcestershire Acute Hospitals NHS Trust, Worcester, UK.
  • Ralston SH; Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
  • Reed MR; Wansbeck General Hospital, Northumbria Healthcare NHS Foundation Trust, Ashington, UK.
  • Riancho JA; Department of Internal Medicine, Hospital U.M. Valdecilla-IFIMAV, University of Cantabria, Santander, Spain.
  • Rivadeneira F; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Rodriguez-Fontenla C; Laboratorio Investigacion 10 and Rheumatology Unit, Instituto de Investigacion Sanitaria-Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain.
  • Southam L; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Thorsteinsdottir U; Department of Population Genetics, deCODE Genetics, Reykjavik, Iceland Department of Medicine, The National University Hospital of Iceland, Reykjavik, Iceland.
  • Tsezou A; Department of Biology, University of Thessaly, Medical School, Larissa, Greece.
  • Wallis GA; Wellcome Trust Centre for Cell-Matrix Research, University of Manchester, Manchester, UK.
Ann Rheum Dis ; 73(12): 2130-6, 2014 Dec.
Article em En | MEDLINE | ID: mdl-23989986
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoartrite do Quadril Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Female / Humans / Male Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoartrite do Quadril Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Female / Humans / Male Idioma: En Ano de publicação: 2014 Tipo de documento: Article