Functional connectivity in the developing brain: a longitudinal study from 4 to 9months of age.
Neuroimage
; 84: 169-80, 2014 Jan 01.
Article
em En
| MEDLINE
| ID: mdl-23994454
ABSTRACT
We characterize the development of intrinsic connectivity networks (ICNs) from 4 to 9months of age with resting state magnetic resonance imaging performed on sleeping infants without sedative medication. Data is analyzed with independent component analysis (ICA). Using both low (30 components) and high (100 components) ICA model order decompositions, we find that the functional network connectivity (FNC) map is largely similar at both 4 and 9months. However at 9months the connectivity strength decreases within local networks and increases between more distant networks. The connectivity within the default-mode network, which contains both local and more distant nodes, also increases in strength with age. The low frequency power spectrum increases with age only in the posterior cingulate cortex and posterior default mode network. These findings are consistent with a general developmental pattern of increasing longer distance functional connectivity over the first year of life and raise questions regarding the developmental importance of the posterior cingulate at this age.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Sono
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Encéfalo
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Envelhecimento
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Interpretação de Imagem Assistida por Computador
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Conectoma
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Rede Nervosa
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Plasticidade Neuronal
Tipo de estudo:
Diagnostic_studies
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Observational_studies
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Prognostic_studies
Limite:
Child
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Child, preschool
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article