Phylogenetic and epidemiologic evidence of multiyear incubation in human rabies.
Ann Neurol
; 75(1): 155-60, 2014 Jan.
Article
em En
| MEDLINE
| ID: mdl-24038455
ABSTRACT
Eight years after emigrating from Brazil, an otherwise healthy man developed rabies. An exposure prior to immigration was reported. Genetic analysis revealed a canine rabies virus variant found only in the patient's home country, and the patient had not traveled internationally since immigrating to the United States. We describe how epidemiological, phylogenetic, and viral sequencing data provided confirmation that rabies encephalomyelitis may present after a long, multiyear incubation period, a consideration that previously has been hypothesized without the ability to exclude a more recent exposure. Accordingly, rabies should be considered in the diagnosis of any acute encephalitis, myelitis, or encephalomyelitis.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Filogenia
/
Raiva
/
Emigrantes e Imigrantes
/
Período de Incubação de Doenças Infecciosas
Limite:
Adult
/
Animals
/
Humans
/
Male
País como assunto:
America do norte
/
America do sul
/
Brasil
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article