Identification of two severe fever with thrombocytopenia syndrome virus strains originating from reassortment.
Virus Res
; 178(2): 543-6, 2013 Dec 26.
Article
em En
| MEDLINE
| ID: mdl-24055465
Recently, a novel bunyavirus, severe fever with thrombocytopenia syndrome virus (SFTSV), was isolated in central China. The virus can cause multi-clinical symptoms: severe fever, thrombocytopenia, leukocytopenia, with a mortality rate of ~10%. Several studies show that SFTSV could undergo rapid evolution via gene mutation and homologous recombination. However, as an important evolutionary force for segmented-genome viruses, reassortment has not been reported in SFTSV. In this study, we identified two SFTSV strains of which the S segment has different origin from M and L, suggesting that reassortment might be potential force driving rapid change of SFTSV. This result might shed new light on the evolutionary behavior of the novel virus.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Vírus Reordenados
/
Phlebovirus
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article