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Identification of two severe fever with thrombocytopenia syndrome virus strains originating from reassortment.
Ding, Nai-Zheng; Luo, Zhi-Fei; Niu, Dan-Dan; Ji, Wei; Kang, Xiu-Han; Cai, Si-Si; Xu, Dong-Shuai; Wang, Qiu-Wen; He, Cheng-Qiang.
Afiliação
  • Ding NZ; College of Life Science, Shandong Normal University, Jinan 250014, China.
Virus Res ; 178(2): 543-6, 2013 Dec 26.
Article em En | MEDLINE | ID: mdl-24055465
Recently, a novel bunyavirus, severe fever with thrombocytopenia syndrome virus (SFTSV), was isolated in central China. The virus can cause multi-clinical symptoms: severe fever, thrombocytopenia, leukocytopenia, with a mortality rate of ~10%. Several studies show that SFTSV could undergo rapid evolution via gene mutation and homologous recombination. However, as an important evolutionary force for segmented-genome viruses, reassortment has not been reported in SFTSV. In this study, we identified two SFTSV strains of which the S segment has different origin from M and L, suggesting that reassortment might be potential force driving rapid change of SFTSV. This result might shed new light on the evolutionary behavior of the novel virus.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vírus Reordenados / Phlebovirus Tipo de estudo: Diagnostic_studies Limite: Humans País como assunto: Asia Idioma: En Ano de publicação: 2013 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vírus Reordenados / Phlebovirus Tipo de estudo: Diagnostic_studies Limite: Humans País como assunto: Asia Idioma: En Ano de publicação: 2013 Tipo de documento: Article