Highly prevalent colorectal cancer-infiltrating LAPâº Foxp3â» T cells exhibit more potent immunosuppressive activity than Foxp3âº regulatory T cells.

Scurr, M; Ladell, K; Besneux, M; Christian, A; Hockey, T; Smart, K; Bridgeman, H; Hargest, R; Phillips, S; Davies, M; Price, D; Gallimore, A; Godkin, A

Highly prevalent colorectal cancer-infiltrating LAPâº Foxp3â» T cells exhibit more potent immunosuppressive activity than Foxp3âº regulatory T cells.

Scurr, M; Ladell, K; Besneux, M; Christian, A; Hockey, T; Smart, K; Bridgeman, H; Hargest, R; Phillips, S; Davies, M; Price, D; Gallimore, A; Godkin, A.

Afiliação

Scurr M; Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Ladell K; Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Besneux M; Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Christian A; Department of Pathology, University Hospital of Wales, Cardiff, UK.
Hockey T; Department of Pathology, University Hospital of Wales, Cardiff, UK.
Smart K; Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Bridgeman H; Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Hargest R; Department of Surgery, University Hospital of Wales, Cardiff, UK.
Phillips S; Department of Surgery, University Hospital of Wales, Cardiff, UK.
Davies M; Department of Surgery, University Hospital of Wales, Cardiff, UK.
Price D; Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Gallimore A; Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Godkin A; Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.

Mucosal Immunol ; 7(2): 428-39, 2014 Mar.

Article em En | MEDLINE | ID: mdl-24064667

Assuntos

Neoplasias Colorretais/imunologia; Neoplasias Colorretais/metabolismo; Linfócitos do Interstício Tumoral/imunologia; Linfócitos do Interstício Tumoral/metabolismo; Linfócitos T Reguladores/imunologia; Linfócitos T Reguladores/metabolismo; Adulto; Idoso; Idoso de 80 Anos ou mais; Antígenos CD/metabolismo; Neoplasias Colorretais/patologia; Feminino; Fatores de Transcrição Forkhead/metabolismo; Humanos; Imunofenotipagem; Proteína Coestimuladora de Linfócitos T Induzíveis/metabolismo; Cadeias alfa de Integrinas/metabolismo; Interleucina-10/biossíntese; Masculino; Pessoa de Meia-Idade; Estadiamento de Neoplasias; Fenótipo; Subpopulações de Linfócitos T/imunologia; Subpopulações de Linfócitos T/metabolismo; Fator de Crescimento Transformador beta/biossíntese; Proteína do Gene 3 de Ativação de Linfócitos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Linfócitos do Interstício Tumoral / Linfócitos T Reguladores Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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