Exchange transfusion as a life-saving intervention in three patients with different haematological malignancies with severe hyperleukocytosis where leukapheresis was not available.
Transfus Apher Sci
; 49(3): 397-402, 2013 Dec.
Article
em En
| MEDLINE
| ID: mdl-24100166
ABSTRACT
Hyperleukocytosis is a rare but potentially serious complication of haematological malignancies. It is usually treated with rehydration, prevention of tumour lysis syndrome and the administration of cytotoxic therapy. Leukapheresis may be life-saving in emergency cases. In this article we describe how, in a resource-limited setting where leukapheresis was not available, manual exchange transfusion was utilised as a life-saving intervention in three patients with different haematological malignancies complicated by hyperleukocytosis. Further we outline the procedure that was carried out and evaluated possible complications associated with this rarely used practice.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Transfusão Total
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Leucaférese
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Neoplasias Hematológicas
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Leucocitose
Tipo de estudo:
Guideline
Limite:
Adult
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article