Effectiveness of melatonin for sleep impairment post paediatric acquired brain injury: evidence from a systematic review.
Dev Neurorehabil
; 17(5): 355-62, 2014 Oct.
Article
em En
| MEDLINE
| ID: mdl-24102301
ABSTRACT
OBJECTIVE:
To retrieve and review all the relevant literature describing the administration of melatonin to treat impaired sleep in children following acquired brain injury (ABI).METHODS:
A systematic search and retrieval of the literature was conducted using advanced search techniques. The retrieval identified 589 papers, seven of which were relevant. Review/outcomes criteria were developed and study quality was determined.RESULTS:
There is paucity of high-quality evidence to support use of melatonin for sleep impairment post paediatric ABI. Variation in dosage, screening and outcome measures, data reporting and a lack of impairment delineation and treatment stratification were recurrent themes.CONCLUSION:
Retrieved evidence for the effectiveness of melatonin for post paediatric ABI sleep impairment appears promising. There is a clear need for further study in this area to inform clinical and research practices. Recommendations are given.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Transtornos do Sono-Vigília
/
Lesões Encefálicas
/
Melatonina
Tipo de estudo:
Guideline
/
Prognostic_studies
/
Systematic_reviews
Limite:
Adolescent
/
Child
/
Child, preschool
/
Humans
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article