Assessment of the flow velocity of blood cells in a microfluidic device using joint spectral and time domain optical coherence tomography.
Opt Express
; 21(20): 24025-38, 2013 Oct 07.
Article
em En
| MEDLINE
| ID: mdl-24104312
ABSTRACT
Although Doppler optical coherence tomography techniques have enabled the imaging of blood flow in mid-sized vessels in biological tissues, the generation of velocity maps of capillary networks remains a challenge. To better understand the origin and information content of the Doppler signal from small vessels and limitations of such measurements, we used joint spectral and time domain optical coherence tomography to monitor the flow in a model, semitransparent microchannel device. The results obtained for Intralipid, whole blood, as well as separated red blood cells indicate that the technique is suitable to record velocity profiles in vitro, in a range of microchannel configurations.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tomografia de Coerência Óptica
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Técnicas Analíticas Microfluídicas
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Eritrócitos
Tipo de estudo:
Prognostic_studies
Limite:
Adult
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Humans
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article