[Ante-natal corticosteroids and prevention of respiratory distress in the premature newborn: usefulness of rescue treatment]. / Corticoides antenatales y prevención del distrés respiratorio del recién nacido prematuro: utilidad de la terapia de rescate.
An Pediatr (Barc)
; 81(2): 120-4, 2014 Aug.
Article
em Es
| MEDLINE
| ID: mdl-24113118
ABSTRACT
The effectiveness of antenatal corticosteroid therapy for foetal lung maturation in pre-term infants is well known, but there is uncertainty about the time that the treatment remains effective. A descriptive, longitudinal study was conducted to determine whether the need for surfactant administration was determined by the time-lapse between corticosteroids administration and delivery, and when repeating the doses of maternal corticosteroids should be considered. A total of 91 premature infants ≤32 weeks and/or ≤1,500 g (limit 34+6 weeks) whose mothers had received a complete course of corticosteroids were included. In patients at 27-34+6 weeks, we found that the longer the time elapsed between delivery and administration of corticosteroids, most likely were the babies to require treatment with surfactant (P=.027). The resulting ROC curve determined an 8-days cut-off after which repeating a dose of corticosteroids should be assessed.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Cuidado Pré-Natal
/
Síndrome do Desconforto Respiratório do Recém-Nascido
/
Betametasona
/
Glucocorticoides
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Female
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Humans
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Male
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Pregnancy
Idioma:
Es
Ano de publicação:
2014
Tipo de documento:
Article