IFN-Î³-driven intratumoral microenvironment exhibits superior prognostic effect compared with an IFN-&#945;-driven microenvironment in patients with colon carcinoma.

Grenz, Sandra; Naschberger, Elisabeth; Merkel, Susanne; Britzen-Laurent, Nathalie; Schaal, Ute; Konrad, Andreas; Aigner, Michael; Rau, Tilman T; Hartmann, Arndt; Croner, Roland S; Hohenberger, Werner; Stürzl, Michael

IFN-Î³-driven intratumoral microenvironment exhibits superior prognostic effect compared with an IFN-α-driven microenvironment in patients with colon carcinoma.

Grenz, Sandra; Naschberger, Elisabeth; Merkel, Susanne; Britzen-Laurent, Nathalie; Schaal, Ute; Konrad, Andreas; Aigner, Michael; Rau, Tilman T; Hartmann, Arndt; Croner, Roland S; Hohenberger, Werner; Stürzl, Michael.

Afiliação

Grenz S; Division of Molecular and Experimental Surgery, Department of Surgery, University Medical Center Erlangen, Erlangen, Germany.
Naschberger E; Division of Molecular and Experimental Surgery, Department of Surgery, University Medical Center Erlangen, Erlangen, Germany.
Merkel S; Department of Internal Medicine 5, University Medical Center Erlangen, Erlangen, Germany.
Britzen-Laurent N; Division of Molecular and Experimental Surgery, Department of Surgery, University Medical Center Erlangen, Erlangen, Germany.
Schaal U; Division of Molecular and Experimental Surgery, Department of Surgery, University Medical Center Erlangen, Erlangen, Germany.
Konrad A; Division of Molecular and Experimental Surgery, Department of Surgery, University Medical Center Erlangen, Erlangen, Germany.
Aigner M; Department of Haematology/Oncology, University Medical Center Erlangen, Erlangen, Germany.
Rau TT; Institute of Pathology, University Medical Center Erlangen, Erlangen, Germany.
Hartmann A; Institute of Pathology, University Medical Center Erlangen, Erlangen, Germany.
Croner RS; Department of Internal Medicine 5, University Medical Center Erlangen, Erlangen, Germany.
Hohenberger W; Department of Internal Medicine 5, University Medical Center Erlangen, Erlangen, Germany.
Stürzl M; Division of Molecular and Experimental Surgery, Department of Surgery, University Medical Center Erlangen, Erlangen, Germany. Electronic address: michael.stuerzl@uk-erlangen.de.

Am J Pathol ; 183(6): 1897-1909, 2013 Dec.

Article em En | MEDLINE | ID: mdl-24121019

Assuntos

Neoplasias do Colo; Interferon-alfa/metabolismo; Interferon gama/metabolismo; Proteínas de Neoplasias/metabolismo; Microambiente Tumoral; Adulto; Idoso; Idoso de 80 Anos ou mais; Neoplasias do Colo/metabolismo; Neoplasias do Colo/mortalidade; Neoplasias do Colo/patologia; Citocinas/metabolismo; Intervalo Livre de Doença; Feminino; Seguimentos; Proteínas de Ligação ao GTP/metabolismo; Humanos; Masculino; Pessoa de Meia-Idade; Proteínas de Resistência a Myxovirus/metabolismo; Estudos Retrospectivos; Taxa de Sobrevida

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Interferon gama / Interferon-alfa / Neoplasias do Colo / Microambiente Tumoral / Proteínas de Neoplasias Tipo de estudo: Observational_studies / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2013 Tipo de documento: Article

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