Arterial spin labeling with simultaneous multi-slice echo planar imaging.
Magn Reson Med
; 70(6): 1500-6, 2013 Dec.
Article
em En
| MEDLINE
| ID: mdl-24130105
ABSTRACT
PURPOSE:
Simultaneous multi-slice (SMS) echo planar imaging (EPI) is incorporated into two-dimensional (2D) arterial spin labeling (ASL) imaging to produce more slices for measuring perfusion in a larger region of the brain than currently possible with multi-slice EPI.METHODS:
Pulsed ASL (PASL) preparations using FAIR and QUIPSS II techniques were combined with SMS-EPI. Testing was performed in four subjects at 3 Tesla. Multiband slice acceleration factors (MB) from MB-2 to MB-5 using 40 averages were evaluated. Comparisons were made quantitatively to PASL 2D EPI and qualitatively to PASL 3D GRASE.RESULTS:
In the 12 slice data set, spatial SNR for the perfusion weighted images averaged across subjects was 3.28 and 3.44 for the two sequential MB-1 acquisitions as control comparison, 3.25 for MB-2 and 2.98 for MB-3. The temporal SNR averaged 1.01 and 0.99 for MB-1, 0.89 for MB-2, and 0.78 for MB-3. For whole-brain spatial coverage, the 20 slice data sets could be acquired in narrower time windows, from 874 ms using EPI (MB-1) down to 196 ms using MB-5. SMS-EPI ASL differed from 3D GRASE ASL, which can use background suppression and has less susceptibility artifact as a CPMG SE sequence.CONCLUSION:
SMS-EPI has a major advantage over EPI-based ASL imaging by increasing slice coverage without lengthening the acquisition time window.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Algoritmos
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Interpretação de Imagem Assistida por Computador
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Artérias Cerebrais
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Circulação Cerebrovascular
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Imagem Ecoplanar
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Angiografia por Ressonância Magnética
Tipo de estudo:
Diagnostic_studies
/
Evaluation_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article