Alclofenac in ankylosing spondylitis.
Curr Med Res Opin
; 3(5): 321-8, 1975.
Article
em En
| MEDLINE
| ID: mdl-241601
ABSTRACT
Eighteen patients with definite ankylosing spondylitis were treated with 3 to 4 g. alclofenac daily for up to 8 months in an open trial against previous therapy. Therapeutic efficacy was greater than or equivalent to previous therapy in 10 of 18 patients after 1 month and 8 patients remain on alclofenac. There was a significant increase in symptoms, particularly morning stiffness after 1 month, but they tended to improve with time. Measurement of spinal movements was not found useful. Side-effects were commoner than expected but not serious. Alclofenac may prove a useful alternative drug in the management of ankylosing spondylitis and further trials are indicated.
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Base de dados:
MEDLINE
Assunto principal:
Fenilacetatos
/
Espondilite Anquilosante
Tipo de estudo:
Etiology_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
1975
Tipo de documento:
Article