A population-based review of the feasibility of platinum-based combination chemotherapy after tyrosine kinase inhibition in EGFR mutation positive non-small cell lung cancer patients with advanced disease.

Mariano, Caroline; Bosdet, Ian; Karsan, Aly; Ionescu, Diana; Murray, Nevin; Laskin, Janessa J; Zhai, Yongliang; Melosky, Barbara; Sun, Sophie; Ho, Cheryl

Mariano, Caroline; Bosdet, Ian; Karsan, Aly; Ionescu, Diana; Murray, Nevin; Laskin, Janessa J; Zhai, Yongliang; Melosky, Barbara; Sun, Sophie; Ho, Cheryl.

Afiliação

Mariano C; British Columbia Cancer Agency, Department of Medical Oncology, 600 West 10th Avenue, Vancouver, BC, Canada V5Z 4E6. Electronic address: cmariano@bccancer.bc.ca.
Bosdet I; British Columbia Cancer Agency, Department of Pathology, 600 West 10th Avenue, Vancouver, BC, Canada V5Z 4E6.
Karsan A; British Columbia Cancer Agency, Department of Pathology, 600 West 10th Avenue, Vancouver, BC, Canada V5Z 4E6.
Ionescu D; British Columbia Cancer Agency, Department of Pathology, 600 West 10th Avenue, Vancouver, BC, Canada V5Z 4E6.
Murray N; British Columbia Cancer Agency, Department of Medical Oncology, 600 West 10th Avenue, Vancouver, BC, Canada V5Z 4E6.
Laskin JJ; British Columbia Cancer Agency, Department of Medical Oncology, 600 West 10th Avenue, Vancouver, BC, Canada V5Z 4E6.
Zhai Y; Department of Statistics, University of British Columbia, Canada.
Melosky B; British Columbia Cancer Agency, Department of Medical Oncology, 600 West 10th Avenue, Vancouver, BC, Canada V5Z 4E6.
Sun S; British Columbia Cancer Agency, Department of Medical Oncology, 600 West 10th Avenue, Vancouver, BC, Canada V5Z 4E6.
Ho C; British Columbia Cancer Agency, Department of Medical Oncology, 600 West 10th Avenue, Vancouver, BC, Canada V5Z 4E6.

Lung Cancer ; 83(1): 73-7, 2014 Jan.

Article em En | MEDLINE | ID: mdl-24192511

Assuntos

Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico; Carcinoma Pulmonar de Células não Pequenas/tratamento farmacológico; Neoplasias Pulmonares/tratamento farmacológico; Compostos de Platina/uso terapêutico; Idoso; Carboplatina/administração & dosagem; Carboplatina/efeitos adversos; Carcinoma Pulmonar de Células não Pequenas/genética; Receptores ErbB/genética; Estudos de Viabilidade; Feminino; Gefitinibe; Humanos; Neoplasias Pulmonares/genética; Masculino; Mutação/genética; Paclitaxel/administração & dosagem; Paclitaxel/efeitos adversos; Grupos Populacionais; Quinazolinas/administração & dosagem; Quinazolinas/efeitos adversos

Palavras-chave

Chemotherapy; EGFR; Gefitinib; Population-based; Second-line; TKI

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Compostos de Platina / Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Aged / Female / Humans / Male Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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