Population genomic analysis reveals no evidence for GC-biased gene conversion in Drosophila melanogaster.
Mol Biol Evol
; 31(2): 425-33, 2014 Feb.
Article
em En
| MEDLINE
| ID: mdl-24214536
ABSTRACT
Gene conversion is the nonreciprocal exchange of genetic material between homologous chromosomes. Multiple lines of evidence from a variety of taxa strongly suggest that gene conversion events are biased toward GC-bearing alleles. However, in Drosophila, the data have largely been indirect and unclear, with some studies supporting the predictions of a GC-biased gene conversion model and other data showing contradictory findings. Here, we test whether gene conversion events are GC-biased in Drosophila melanogaster using whole-genome polymorphism and divergence data. Our results provide no support for GC-biased gene conversion and thus suggest that this process is unlikely to significantly contribute to patterns of polymorphism and divergence in this system.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Citosina
/
Drosophila melanogaster
/
Conversão Gênica
/
Guanina
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article