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Immunization with either prion protein fragment 95-123 or the fragment-specific antibodies rescue memory loss and neurodegenerative phenotype of neurons in olfactory bulbectomized mice.
Bobkova, N V; Medvinskaya, N I; Kamynina, A V; Aleksandrova, I Y; Nesterova, I V; Samokhin, A N; Koroev, D O; Filatova, M P; Nekrasov, P V; Abramov, A Y; Leonov, S V; Volpina, O M.
Afiliação
  • Bobkova NV; Institute of Cell Biophysics, Russian Academy of Sciences, ul. Institutskaya, 3. Pushchino, Russia. Electronic address: nbobkova@mail.ru.
  • Medvinskaya NI; Institute of Cell Biophysics, Russian Academy of Sciences, ul. Institutskaya, 3. Pushchino, Russia. Electronic address: nmedvinskaya@rambler.ru.
  • Kamynina AV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya, 16/10, 117997 Moscow, Russia. Electronic address: aneskaminina@mail.ru.
  • Aleksandrova IY; Institute of Cell Biophysics, Russian Academy of Sciences, ul. Institutskaya, 3. Pushchino, Russia. Electronic address: iualex@rambler.ru.
  • Nesterova IV; Institute of Cell Biophysics, Russian Academy of Sciences, ul. Institutskaya, 3. Pushchino, Russia. Electronic address: nprivat@rambler.ru.
  • Samokhin AN; Institute of Cell Biophysics, Russian Academy of Sciences, ul. Institutskaya, 3. Pushchino, Russia. Electronic address: sam.alexandre@gmail.com.
  • Koroev DO; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya, 16/10, 117997 Moscow, Russia. Electronic address: koroev@mx.ibch.ru.
  • Filatova MP; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya, 16/10, 117997 Moscow, Russia. Electronic address: filatova07@mail.ru.
  • Nekrasov PV; Institute of Cell Biophysics, Russian Academy of Sciences, ul. Institutskaya, 3. Pushchino, Russia. Electronic address: pgta01@mail.ru.
  • Abramov AY; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, WC1N 3BG London, UK. Electronic address: a.abramov@ucl.ac.uk.
  • Leonov SV; Institute of Cell Biophysics, Russian Academy of Sciences, ul. Institutskaya, 3. Pushchino, Russia; Department of Biology, Chemical Diversity Research Institute (CDRI), Rabochaya St., 2-A, 141400 Khimki, Moscow Region, Russia; BioBusiness Incubator, Moscow Institute of Physics and Technology, Instit
  • Volpina OM; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya, 16/10, 117997 Moscow, Russia. Electronic address: volpina@ibch.ru.
Neurobiol Learn Mem ; 107: 50-64, 2014 Jan.
Article em En | MEDLINE | ID: mdl-24239620
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Príons / Proteínas PrPC / Fármacos Neuroprotetores / Transtornos da Memória / Degeneração Neural Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Príons / Proteínas PrPC / Fármacos Neuroprotetores / Transtornos da Memória / Degeneração Neural Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article