Anti-proliferative effect of recombinant human endostatin on synovial fibroblasts in rats with adjuvant arthritis.

Huang, Xue-Ying; Zhang, Xiao-Ming; Chen, Fei-Hu; Zhou, Lan-Lan; Deng, Xue-Fei; Liu, Yong-Jing; Li, Xiao-Jing

Huang, Xue-Ying; Zhang, Xiao-Ming; Chen, Fei-Hu; Zhou, Lan-Lan; Deng, Xue-Fei; Liu, Yong-Jing; Li, Xiao-Jing.

Afiliação

Huang XY; School of Pharmacy, Anhui Medical University, 81 Meishan Road, Hefei 230032, China; Department of Anatomy, Anhui Medical University, 81 Meishan Road, Hefei 230032, China. Electronic address: hxy8676@126.com.
Zhang XM; Department of Anatomy, Anhui Medical University, 81 Meishan Road, Hefei 230032, China. Electronic address: zhxm_1919@126.com.
Chen FH; School of Pharmacy, Anhui Medical University, 81 Meishan Road, Hefei 230032, China. Electronic address: cfhchina@sohu.com.
Zhou LL; Department of Pharmacology, Anhui Medical University, 81 Meishan Road, Hefei 230032, China. Electronic address: lanlzhou@aliyun.com.
Deng XF; Department of Anatomy, Anhui Medical University, 81 Meishan Road, Hefei 230032, China. Electronic address: knowou@163.com.
Liu YJ; Department of Cardiothoracic Surgery, PLA 105 Hospital, 424 Changjiang Road, Hefei 230032, China. Electronic address: yongjingliu@163.com.
Li XJ; Department of Plastic Surgery, The First Affiliated Hospital, Anhui Medical University, 218 Jixi Road, Hefei 230022, China. Electronic address: lixiaojing5@163.com.

Eur J Pharmacol ; 723: 7-14, 2014 Jan 15.

Article em En | MEDLINE | ID: mdl-24239715

Assuntos

Antirreumáticos/farmacologia; Artrite Experimental/metabolismo; Endostatinas/farmacologia; Fibroblastos/efeitos dos fármacos; Membrana Sinovial/citologia; Animais; Ciclo Celular/efeitos dos fármacos; Proliferação de Células/efeitos dos fármacos; Células Cultivadas; Ciclina D1/genética; Ciclina D1/metabolismo; Quinase 4 Dependente de Ciclina/genética; Quinase 4 Dependente de Ciclina/metabolismo; Inibidor de Quinase Dependente de Ciclina p21/genética; Inibidor de Quinase Dependente de Ciclina p21/metabolismo; Fibroblastos/citologia; Fibroblastos/metabolismo; Humanos; Masculino; Antígeno Nuclear de Célula em Proliferação/genética; Antígeno Nuclear de Célula em Proliferação/metabolismo; RNA Mensageiro/metabolismo; Ratos; Ratos Sprague-Dawley; Proteínas Recombinantes/farmacologia; Proteína Supressora de Tumor p53/genética; Proteína Supressora de Tumor p53/metabolismo

Palavras-chave

Proliferation; Recombinant human endostatin; Rheumatoid arthritis; Synovial fibroblast

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Experimental / Membrana Sinovial / Antirreumáticos / Endostatinas / Fibroblastos Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google