Multifocal spinal malignant peripheral nerve sheath tumor in an immunocompromised individual: case report and review of literature.
Eur Spine J
; 23 Suppl 2: 236-41, 2014 May.
Article
em En
| MEDLINE
| ID: mdl-24249554
ABSTRACT
PURPOSE:
Primary intraosseous spinal malignant peripheral nerve sheath tumor (MPNST) is exceedingly rare. MPNST with multifocal origin has been described to occur in the extremities. Such a lesion has not been described to occur in the spine. We describe a case of multifocal spinal MPNST and to review the literature relevant to this rare entity and its management.METHODS:
A 40-year-old immunodeficient patient presented with rapidly progressive paraparesis and mid back ache.RESULTS:
Despite aggressive surgical decompression, he developed multiple metastases 3 months after surgery. However, he remained stable for 1 year without any adjuvant therapy. Presently, he has received palliative radiotherapy for spinal recurrence and cerebral metastasis.CONCLUSION:
Multifocal spinal MPNST is a rare lesion. In this instance, the multifocality of the disease and its odd location could be attributed to the immunodeficiency state. The prolonged survival could be due to an improvement in his immune status due to HAART.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Coluna Vertebral
/
Neoplasias Torácicas
/
Neoplasias de Bainha Neural
/
Doenças Raras
Tipo de estudo:
Etiology_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article