GCN2, an old dog with new tricks.
Biochem Soc Trans
; 41(6): 1687-91, 2013 Dec.
Article
em En
| MEDLINE
| ID: mdl-24256275
ABSTRACT
Gcn2 was first described in budding yeast as a serine/threonine protein kinase involved in the response to amino acid starvation and this is its best characterized role to date. Recent work has revealed new and exciting roles for Gcn2, which affect many aspects of cellular physiology in response to a number of stresses in addition to starvation. Furthermore, the Gcn2 pathway has been implicated in diseases such as cancer and Alzheimer's disease, and therefore elucidating the new roles of Gcn2 seems ever more important.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Proteínas Serina-Treonina Quinases
/
Proteínas de Saccharomyces cerevisiae
Limite:
Humans
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article