One-pot palladium-catalyzed borrowing hydrogen synthesis of thioethers.
Chemistry
; 19(51): 17464-71, 2013 Dec 16.
Article
em En
| MEDLINE
| ID: mdl-24259460
ABSTRACT
Palladium on magnesium oxide is able to allow a one-pot reaction to synthesize thioethers from thiols and aldehydes formed in situ from the respective alcohol by means of a borrowing hydrogen method. The reaction is initiated by dehydrogenation of the alcohol to give a palladium hydride intermediate and an aldehyde. The latter reacts with a thiol involving most probably the intermediacy of a thionium ion RCH=S(+)R, which can be reduced in situ by the metal hydride to afford thioethers.
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MEDLINE
Assunto principal:
Paládio
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Hidrogênio
Idioma:
En
Ano de publicação:
2013
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Article