Effect of dNTP pool alterations on fidelity of leading and lagging strand DNA replication in E. coli.

Gawel, Damian; Fijalkowska, Iwona J; Jonczyk, Piotr; Schaaper, Roel M

Gawel, Damian; Fijalkowska, Iwona J; Jonczyk, Piotr; Schaaper, Roel M.

Afiliação

Gawel D; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw 02-106, Poland; Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, United States. Electronic address: gawel@cmkp.edu.pl.
Fijalkowska IJ; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw 02-106, Poland.
Jonczyk P; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw 02-106, Poland.
Schaaper RM; Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, United States.

Mutat Res ; 759: 22-8, 2014 Jan.

Article em En | MEDLINE | ID: mdl-24269257

Assuntos

Replicação do DNA; Desoxirribonucleotídeos/metabolismo; Escherichia coli/genética; Nucleotídeos de Desoxiadenina/metabolismo; Nucleotídeos de Desoxicitosina/metabolismo; Nucleotídeos de Desoxiguanina/metabolismo; Óperon Lac; Nucleotídeos de Timina/metabolismo

Palavras-chave

Base selection; Base·base mispairs; DNA replication fidelity; Exonucleolytic proofreading; Leading and lagging strands; dNTP precursors

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desoxirribonucleotídeos / Replicação do DNA / Escherichia coli Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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