Differential inhibitory effects of cyanovirin-N, griffithsin, and scytovirin on entry mediated by envelopes of gammaretroviruses and deltaretroviruses.
J Virol
; 88(4): 2327-32, 2014 Feb.
Article
em En
| MEDLINE
| ID: mdl-24284326
ABSTRACT
The antiviral lectins griffithsin (GRFT), cyanovirin-N (CV-N), and scytovirin (SVN), which inhibit several enveloped viruses, including lentiviruses, were examined for their ability to inhibit entry mediated by Env proteins of delta- and gammaretroviruses. The glycoproteins from human T-cell leukemia virus type 1 (HTLV-1) were resistant to the antiviral effects of all three lectins. For gammaretroviruses, CV-N inhibited entry mediated by some but not all of the envelopes examined, whereas GRFT and SVN displayed only little or no effect.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Proteínas de Bactérias
/
Vírus Linfotrópico T Tipo 1 Humano
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Proteínas de Transporte
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Proteínas do Envelope Viral
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Gammaretrovirus
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Lectinas de Plantas
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Internalização do Vírus
/
Lectinas
Limite:
Humans
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article