Baseline comprehensive geriatric assessment is associated with toxicity and survival in elderly metastatic breast cancer patients receiving single-agent chemotherapy: results from the OMEGA study of the Dutch breast cancer trialists' group.

Hamaker, M E; Seynaeve, C; Wymenga, A N M; van Tinteren, H; Nortier, J W R; Maartense, E; de Graaf, H; de Jongh, F E; Braun, J J; Los, M; Schrama, J G; van Leeuwen-Stok, A E; de Groot, S M; Smorenburg, C H

Hamaker, M E; Seynaeve, C; Wymenga, A N M; van Tinteren, H; Nortier, J W R; Maartense, E; de Graaf, H; de Jongh, F E; Braun, J J; Los, M; Schrama, J G; van Leeuwen-Stok, A E; de Groot, S M; Smorenburg, C H.

Afiliação

Hamaker ME; Department of Geriatric Medicine, Diakonessenhuis Utrecht, The Netherlands. Electronic address: mhamaker@diakhuis.nl.
Seynaeve C; Department of Medical Oncology, Erasmus University Medical Centre - Daniel den Hoed Cancer Centre, Rotterdam, The Netherlands.
Wymenga AN; Department of Internal Medicine, Medisch Spectrum Twente, Enschede, The Netherlands.
van Tinteren H; Antoni van Leeuwenhoek Hospital/NKI, Amsterdam, The Netherlands.
Nortier JW; Department of Medical Oncology, Leiden University Medical Centre, Leiden, The Netherlands.
Maartense E; Department of Internal Medicine, Reinier de Graaf Hospital, Delft, The Netherlands.
de Graaf H; Department of Medical Oncology, Medical Center Leeuwarden, Leeuwarden, The Netherlands.
de Jongh FE; Department of Internal Medicine, Ikazia Hospital, Rotterdam, The Netherlands.
Braun JJ; Department of Internal Medicine, Vlietland Hospital, Schiedam, The Netherlands.
Los M; Department of Internal Medicine, St. Antonius Hospital, Nieuwegein, The Netherlands.
Schrama JG; Department of Internal Medicine, Spaarne Hospital, Hoofddorp, The Netherlands.
van Leeuwen-Stok AE; Dutch Breast Cancer Trialists' Group BOOG, Amsterdam, The Netherlands.
de Groot SM; Dutch Breast Cancer Trialists' Group BOOG/Comprehensive Cancer Center, Amsterdam, The Netherlands.
Smorenburg CH; Department of Internal Medicine, Medical Centre Alkmaar, The Netherlands.

Breast ; 23(1): 81-7, 2014 Feb.

Article em En | MEDLINE | ID: mdl-24314824

Assuntos

Antineoplásicos/efeitos adversos; Neoplasias da Mama/tratamento farmacológico; Desoxicitidina/análogos & derivados; Doxorrubicina/análogos & derivados; Fluoruracila/análogos & derivados; Avaliação Geriátrica; Atividades Cotidianas; Idoso; Idoso de 80 Anos ou mais; Antineoplásicos/uso terapêutico; Índice de Massa Corporal; Neoplasias da Mama/epidemiologia; Neoplasias da Mama/patologia; Capecitabina; Transtornos Cognitivos/epidemiologia; Comorbidade; Desoxicitidina/efeitos adversos; Desoxicitidina/uso terapêutico; Depressão/epidemiologia; Doxorrubicina/efeitos adversos; Doxorrubicina/uso terapêutico; Fadiga/induzido quimicamente; Feminino; Fluoruracila/efeitos adversos; Fluoruracila/uso terapêutico; Idoso Fragilizado; Síndrome Mão-Pé/etiologia; Humanos; Entrevista Psiquiátrica Padronizada; Cuidados Paliativos; Polietilenoglicóis/efeitos adversos; Polietilenoglicóis/uso terapêutico; Polimedicação; Fatores de Risco; Estomatite/induzido quimicamente; Resultado do Tratamento

Palavras-chave

Geriatric assessment; Metastatic breast cancer; Palliative chemotherapy

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Doxorrubicina / Avaliação Geriátrica / Desoxicitidina / Fluoruracila / Antineoplásicos Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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