NAMPT (visfatin), a direct target of hypoxia-inducible factor-2&#945;, is an essential catabolic regulator of osteoarthritis.

Yang, Siyoung; Ryu, Je-Hwang; Oh, Hwanhee; Jeon, Jimin; Kwak, Ji-Sun; Kim, Jin-Hong; Kim, Hyun Ah; Chun, Churl-Hong; Chun, Jang-Soo

NAMPT (visfatin), a direct target of hypoxia-inducible factor-2α, is an essential catabolic regulator of osteoarthritis.

Yang, Siyoung; Ryu, Je-Hwang; Oh, Hwanhee; Jeon, Jimin; Kwak, Ji-Sun; Kim, Jin-Hong; Kim, Hyun Ah; Chun, Churl-Hong; Chun, Jang-Soo.

Afiliação

Yang S; Cell Dynamics Research Center and School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Korea Division of Immunology, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, USA.
Ryu JH; Research Center for Biomineralization Disorders and Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju, Korea.
Oh H; Cell Dynamics Research Center and School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Korea.
Jeon J; Cell Dynamics Research Center and School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Korea.
Kwak JS; Cell Dynamics Research Center and School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Korea.
Kim JH; Cell Dynamics Research Center and School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Korea.
Kim HA; Division of Rheumatology, Hallym University Sacred Heart Hospital, Kyunggi, Korea.
Chun CH; Department of Orthopedic Surgery, Wonkwang University School of Medicine, Iksan, Korea.
Chun JS; Cell Dynamics Research Center and School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Korea.

Ann Rheum Dis ; 74(3): 595-602, 2015 Mar.

Article em En | MEDLINE | ID: mdl-24347567

Assuntos

Artrite Experimental/metabolismo; Fatores de Transcrição Hélice-Alça-Hélice Básicos/metabolismo; Cartilagem Articular/metabolismo; Condrócitos/metabolismo; Colágeno Tipo II/metabolismo; Nicotinamida Fosforribosiltransferase/metabolismo; Osteoartrite/metabolismo; Agrecanas/metabolismo; Animais; Cartilagem Articular/citologia; Humanos; Metaloproteinases da Matriz/metabolismo; Meniscos Tibiais/cirurgia; Camundongos; Camundongos Endogâmicos C57BL; Regulação para Cima

Palavras-chave

Chondrocytes; Cytokines; Knee Osteoarthritis; Osteoarthritis; Synovitis

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoartrite / Artrite Experimental / Cartilagem Articular / Condrócitos / Colágeno Tipo II / Fatores de Transcrição Hélice-Alça-Hélice Básicos / Nicotinamida Fosforribosiltransferase Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google