Two distinct phenotypes in pigmented cells of different embryonic origins in eyes of pale ear mice.

Jing, Renwei; Dong, Xuan; Li, Kailin; Zhang, Jingye; Yan, Jie; Feng, Lijun

Jing, Renwei; Dong, Xuan; Li, Kailin; Zhang, Jingye; Yan, Jie; Feng, Lijun.

Afiliação

Jing R; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, Institute of Developmental Biology, School of Life Sciences, Shandong University, Jinan, Shandong 250100, PR China.
Dong X; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, Institute of Developmental Biology, School of Life Sciences, Shandong University, Jinan, Shandong 250100, PR China.
Li K; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, Institute of Developmental Biology, School of Life Sciences, Shandong University, Jinan, Shandong 250100, PR China.
Zhang J; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, Institute of Developmental Biology, School of Life Sciences, Shandong University, Jinan, Shandong 250100, PR China.
Yan J; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, Institute of Developmental Biology, School of Life Sciences, Shandong University, Jinan, Shandong 250100, PR China.
Feng L; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, Institute of Developmental Biology, School of Life Sciences, Shandong University, Jinan, Shandong 250100, PR China. Electronic address: drfeng@sdu.edu.cn.

Exp Eye Res ; 119: 35-43, 2014 Feb.

Article em En | MEDLINE | ID: mdl-24361037

Assuntos

Síndrome de Hermanski-Pudlak/patologia; Melanossomas/ultraestrutura; Epitélio Pigmentado da Retina/embriologia; Animais; Western Blotting; Modelos Animais de Doenças; Síndrome de Hermanski-Pudlak/genética; Síndrome de Hermanski-Pudlak/metabolismo; Melanossomas/enzimologia; Camundongos; Camundongos Endogâmicos C57BL; Microscopia Eletrônica de Transmissão; Monofenol Mono-Oxigenase/metabolismo; Fenótipo; Epitélio Pigmentado da Retina/enzimologia; Epitélio Pigmentado da Retina/ultraestrutura

Palavras-chave

A-CPE; A-IPE; ASM; B6; BLOC-3; C57BL-6J; HPS; HermanskyPudlak syndrome; LROs; P; P-CNE; P-IPE; RPE; SEM; TYR; alkali-soluble melanin; anterior ciliary pigment epithelium; anterior iris pigment epithelium; biogenesis of lysosome-related organelle complex 3; development; ep; hypopigmentation; l-3,4-Dihydroxyphenylalanine; l-DOPA; lipofuscin; lysosome related organelles; macromelanosome; pale ear; posterior ciliary non pigment epithelium; posterior iris pigment epithelium; postnatal day; retinal pigment epithelium; standard error of the mean; tyrosinase

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Melanossomas / Síndrome de Hermanski-Pudlak / Epitélio Pigmentado da Retina Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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