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Developing novel blood-based biomarkers for Alzheimer's disease.
Snyder, Heather M; Carrillo, Maria C; Grodstein, Francine; Henriksen, Kim; Jeromin, Andreas; Lovestone, Simon; Mielke, Michelle M; O'Bryant, Sid; Sarasa, Manual; Sjøgren, Magnus; Soares, Holly; Teeling, Jessica; Trushina, Eugenia; Ward, Malcolm; West, Tim; Bain, Lisa J; Shineman, Diana W; Weiner, Michael; Fillit, Howard M.
Afiliação
  • Snyder HM; Medical and Scientific Relations, Alzheimer's Association, Chicago, IL, USA. Electronic address: hsnyder@alz.org.
  • Carrillo MC; Medical and Scientific Relations, Alzheimer's Association, Chicago, IL, USA.
  • Grodstein F; Department of Medicine, Brigham and Women's Hospital, Inc., Boston, MA, USA.
  • Henriksen K; Biomarker and Research Division, Nordic Biosciences, Copenhagen, Denmark.
  • Jeromin A; NextGen Sciences Dx, Gainesville, FL, USA.
  • Lovestone S; Institute of Psychiatry, Department of Medicine and Neurosciences, King's College, London, UK.
  • Mielke MM; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
  • O'Bryant S; Internal Medicine Department, University of North Texas Health Sciences Center at Fort Worth, Fort Worth, TX, USA.
  • Sarasa M; Araclon Biotech, Zaragoza, Spain.
  • Sjøgren M; Diagenic ASA, Oslo, Norway.
  • Soares H; Bristol Myers Squibb, Co., Wallingford, CT, USA.
  • Teeling J; University of Southampton, Southampton, UK.
  • Trushina E; Department of Neurology, Mayo Clinic, Rochester, MN, USA.
  • Ward M; Proteome Sciences plc, London, UK.
  • West T; C2N Diagnostics, St Louis, MO, USA.
  • Bain LJ; Independent Science Writer, Philadelphia, PA, USA.
  • Shineman DW; Alzheimer's Drug Discovery Foundation, New York, NY, USA.
  • Weiner M; School of Medicine, University of California-San Francisco, San Francisco, CA, USA; Department of Veterans Affairs Medical Center, San Francisco, CA, USA.
  • Fillit HM; Alzheimer's Drug Discovery Foundation, New York, NY, USA.
Alzheimers Dement ; 10(1): 109-14, 2014 Jan.
Article em En | MEDLINE | ID: mdl-24365657
ABSTRACT
Alzheimer's disease is the public health crisis of the 21st century. There is a clear need for a widely available, inexpensive and reliable method to diagnosis Alzheimer's disease in the earliest stages, track disease progression, and accelerate clinical development of new therapeutics. One avenue of research being explored is blood based biomarkers. In April 2012, the Alzheimer's Association and the Alzheimer's Drug Discovery Foundation convened top scientists from around the world to discuss the state of blood based biomarker development. This manuscript summarizes the meeting and the resultant discussion, including potential next steps to move this area of research forward.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biomarcadores / Doença de Alzheimer Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biomarcadores / Doença de Alzheimer Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article