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Structural context of disease-associated mutations and putative mechanism of autoinhibition revealed by X-ray crystallographic analysis of the EZH2-SET domain.
Antonysamy, Stephen; Condon, Bradley; Druzina, Zhanna; Bonanno, Jeffrey B; Gheyi, Tarun; Zhang, Feiyu; MacEwan, Iain; Zhang, Aiping; Ashok, Sheela; Rodgers, Logan; Russell, Marijane; Gately Luz, John.
Afiliação
  • Antonysamy S; Lilly Biotechnology Center San Diego, San Diego, California, United States of America.
  • Condon B; Lilly Biotechnology Center San Diego, San Diego, California, United States of America.
  • Druzina Z; Lilly Biotechnology Center San Diego, San Diego, California, United States of America.
  • Bonanno JB; Department of Biochemistry, Albert Einstein College of Medicine University, Jack and Pearl Resnik Campus, Bronx, New York, United States of America.
  • Gheyi T; Lilly Biotechnology Center San Diego, San Diego, California, United States of America.
  • Zhang F; Lilly Biotechnology Center San Diego, San Diego, California, United States of America.
  • MacEwan I; Department of Radiology, Loma Linda University Medical Center, Loma Linda, California, United States of America.
  • Zhang A; Lilly Biotechnology Center San Diego, San Diego, California, United States of America.
  • Ashok S; Lilly Biotechnology Center San Diego, San Diego, California, United States of America.
  • Rodgers L; Lilly Biotechnology Center San Diego, San Diego, California, United States of America.
  • Russell M; Lilly Biotechnology Center San Diego, San Diego, California, United States of America.
  • Gately Luz J; Lilly Biotechnology Center San Diego, San Diego, California, United States of America.
PLoS One ; 8(12): e84147, 2013.
Article em En | MEDLINE | ID: mdl-24367637
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença / Domínio Catalítico / Complexo Repressor Polycomb 2 / Mutação Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2013 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença / Domínio Catalítico / Complexo Repressor Polycomb 2 / Mutação Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2013 Tipo de documento: Article