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Neuroinflammation and α-synuclein accumulation in response to glucocerebrosidase deficiency are accompanied by synaptic dysfunction.
Ginns, Edward I; Mak, Sally K-K; Ko, Novie; Karlgren, Juliane; Akbarian, Schahram; Chou, Vivian P; Guo, Yin; Lim, Arlene; Samuelsson, Steven; LaMarca, Mary L; Vazquez-DeRose, Jacqueline; Manning-Bog, Amy B.
Afiliação
  • Ginns EI; Lysosomal Disorders Treatment and Research Program, Clinical Labs, University of Massachusetts Medical School, Worcester, MA 01545, USA; Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01545, USA; Clinical Neuroscience Branch, IRP, NIMH, Bethesda, MD 20892, USA.
  • Mak SK; Center for Health Sciences, Biosciences Division, SRI International, Menlo Park, CA 94025, USA.
  • Ko N; Center for Health Sciences, Biosciences Division, SRI International, Menlo Park, CA 94025, USA.
  • Karlgren J; Lysosomal Disorders Treatment and Research Program, Clinical Labs, University of Massachusetts Medical School, Worcester, MA 01545, USA.
  • Akbarian S; Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01545, USA.
  • Chou VP; Center for Health Sciences, Biosciences Division, SRI International, Menlo Park, CA 94025, USA.
  • Guo Y; Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01545, USA.
  • Lim A; Lysosomal Disorders Treatment and Research Program, Clinical Labs, University of Massachusetts Medical School, Worcester, MA 01545, USA; Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01545, USA.
  • Samuelsson S; Center for Neuroscience, Biosciences Division, SRI International, Menlo Park, CA 94025, USA.
  • LaMarca ML; Clinical Neuroscience Branch, IRP, NIMH, Bethesda, MD 20892, USA.
  • Vazquez-DeRose J; Center for Neuroscience, Biosciences Division, SRI International, Menlo Park, CA 94025, USA.
  • Manning-Bog AB; Center for Health Sciences, Biosciences Division, SRI International, Menlo Park, CA 94025, USA. Electronic address: amy.manningbog@sri.com.
Mol Genet Metab ; 111(2): 152-62, 2014 Feb.
Article em En | MEDLINE | ID: mdl-24388731
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Sinapses / Corpo Estriado / Alfa-Sinucleína / Doença de Gaucher / Glucosilceramidase Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Sinapses / Corpo Estriado / Alfa-Sinucleína / Doença de Gaucher / Glucosilceramidase Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2014 Tipo de documento: Article