Cross-Species Induction and Enhancement of Antimicrobial Properties in Response to Gamma Irradiation in Exiguobacterium sp. HKG 126.
Indian J Microbiol
; 53(2): 130-6, 2013 Jun.
Article
em En
| MEDLINE
| ID: mdl-24426098
ABSTRACT
A gram positive, extreme haloalkaliphilic, radioresistant bacterium was isolated from mangrove region of Kerala (India) which was characterized as Exiguobacterium sp. HKG-126 using morphological, physiological, biochemical and molecular characterization. Present investigation was undertaken to examine Exiguobacterium sp. as a potential source of broad-spectrum antimicrobial activity and enhancement in this activity was observed due to cross-species/cross-genera induction and also in response to high dose of gamma (γ) irradiation. Individual studies on the antimicrobial activity of all the co-cultivated bacterial strains before and after mixed culture fermentation, showed excellent enhancement in antimicrobial activity of Exiguobacterium sp. against a variety of clinical pathogens. To the best of our knowledge, this is the first report showing existence of an extremely high radioresistant strain of (up to 15 kGy) Exiguobacterium sp.
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MEDLINE
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En
Ano de publicação:
2013
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Article