Room temperature decarboxylative trifluoromethylation of α,ß-unsaturated carboxylic acids by photoredox catalysis.
Chem Commun (Camb)
; 50(18): 2308-10, 2014 Mar 04.
Article
em En
| MEDLINE
| ID: mdl-24445904
ABSTRACT
A visible-light-induced decarboxylative trifluoromethylation of α,ß-unsaturated carboxylic acids, which uses the Togni reagent as the CF3 source is disclosed. The corresponding trifluoromethylated alkenes were obtained in moderate to high yields with excellent functional group tolerance at ambient temperature. Preliminary mechanistic analyses suggest a radical-type mechanism.
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1
Base de dados:
MEDLINE
Assunto principal:
Temperatura
/
Ácidos Carboxílicos
/
Hidrocarbonetos Fluorados
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article