n-3 LC-PUFA supplementation: effects on infant and maternal outcomes.
Eur J Nutr
; 53(5): 1147-54, 2014 Aug.
Article
em En
| MEDLINE
| ID: mdl-24448975
ABSTRACT
BACKGROUND:
Long-chain polyunsaturated fatty acids (LC-PUFA), particularly docosahexaenoic acid (DHA) and arachidonic acid, are, respectively, n-3 and n-6 family members and play an important role in fetal and infant growth and development. Pregnancy and lactation impose special nutritional needs for the mother-fetus situation. Since the LC-PUFA required by the fetus is supplied by preferential placental transfer of preformed LC-PUFA rather than their precursor, it has been hypothesized that additional maternal supply of LC-PUFA, especially DHA, during pregnancy may improve maternal and infant outcomes.AIM:
To summarize evidences of the effect of n-3 LC-PUFA intake during pregnancy and lactation on maternal and infant outcomes in order to offer a comprehensive view of this issue that should be useful for clinical practice.RESULTS:
Maternal n-3 LC-PUFA supplementation may reduce risk for early preterm birth >34 weeks and seems very promising for primary allergy prevention during childhood. On the contrary, there are not sufficient data proving that the consumption of oils rich in n-3 LC-PUFA during pregnancy optimizes child's visual and neurodevelopment and reduces the risk for preeclampsia and perinatal depression; the implications of these findings remain to be elucidated.CONCLUSION:
The implications of n-3 LC-PUFA supplementation on fetal development, maternal outcomes and later infant growth is worth being elucidated and is promising in its potential for a positive impact on fetal and maternal outcomes.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ácidos Graxos Ômega-3
/
Suplementos Nutricionais
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Fenômenos Fisiológicos da Nutrição Materna
Tipo de estudo:
Clinical_trials
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Observational_studies
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Systematic_reviews
Limite:
Female
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Humans
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Infant
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Pregnancy
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article