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Cinchona alkaloids from Cinchona succirubra and Cinchona ledgeriana.
Cheng, Gui-Guang; Cai, Xiang-Hai; Zhang, Bao-Hong; Li, Yan; Gu, Ji; Bao, Mei-Fen; Liu, Ya-Ping; Luo, Xiao-Dong.
Afiliação
  • Cheng GG; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P. R. China.
  • Cai XH; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P. R. China.
  • Zhang BH; Yunnan University of Traditional Chinese Medicine, Kunming, P. R. China.
  • Li Y; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P. R. China.
  • Gu J; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P. R. China.
  • Bao MF; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P. R. China.
  • Liu YP; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P. R. China.
  • Luo XD; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P. R. China.
Planta Med ; 80(2-3): 223-30, 2014 Feb.
Article em En | MEDLINE | ID: mdl-24452461
ABSTRACT
Seven new cinchona alkaloids, cinchonanines A-G (1-7), and 29 known alkaloids were isolated from the barks of Cinchona surrirubra and C. ledgeriana collected from Yunnan Province in China. The new structures were elucidated by extensive spectroscopic analysis. All compounds were evaluated for their cytotoxicity against five human cancer cell lines. Compounds 2, 13, 14, and 15 showed moderate cytotoxicity.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cinchona / Alcaloides de Cinchona / Citotoxinas Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cinchona / Alcaloides de Cinchona / Citotoxinas Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article