A quantitative trait locus for ascites on chromosome 9 in broiler chicken lines.
Poult Sci
; 93(2): 307-17, 2014 Feb.
Article
em En
| MEDLINE
| ID: mdl-24570451
ABSTRACT
A genome-wide SNP survey was used to identify chromosomal regions that showed linkage disequilibrium with respect to ascites susceptibility and ventricular hypertrophy in an F2 cross between previously described ascites-resistant and -susceptible lines. Variable number tandem repeats were used to obtain genotype data to further characterize these regions. A region on chromosome 9 (12 to 13 Mbp in 2011 assembly) shows association with ascites in the ascites lines and in several commercial broiler breeder lines with a significant sex effect. There are 2 candidate genes, AGTR1 (an angiotensin II type 1 receptor) and UTS2D (urotensin 2 domain containing), in this region that have been associated with hypertension and hypoxic response in mammals.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças das Aves Domésticas
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Ascite
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Galinhas
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Cardiomegalia
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Proteínas Aviárias
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Hormônios Peptídicos
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Receptor Tipo 1 de Angiotensina
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article