Sperm cryopreservation before testicular cancer treatment and its subsequent utilization for the treatment of infertility.
ScientificWorldJournal
; 2014: 575978, 2014.
Article
em En
| MEDLINE
| ID: mdl-24587730
ABSTRACT
AIMS:
In this study we report our results with storage of cryopreserved semen intended for preservation and subsequent infertility treatment in men with testicular cancer during the last 18 years.METHODS:
Cryopreserved semen of 523 men with testicular cancer was collected between October 1995 and the end of December 2012. Semen of 34 men (6.5%) was used for fertilization of their partners. They underwent 57 treatment cycles with cryopreserved, fresh, and/or donor sperm.RESULTS:
A total of 557 men have decided to freeze their semen before cancer treatment. Azoospermia was diagnosed in 34 men (6.1%), and semen was cryopreserved in 532 patients. Seminoma was diagnosed in 283 men (54.1%) and nonseminomatous germ cell tumors in 240 men (45.9%). 34 patients who returned for infertility treatment underwent 46 treatment cycles with cryopreserved sperm. Totally 16 pregnancies were achieved, that is, 34.8% pregnancy rate.CONCLUSION:
The testicular cancer survivors have a good chance of fathering a child by using sperm cryopreserved prior to the oncology treatment, even when it contains only limited number of spermatozoa.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Espermatozoides
/
Neoplasias Testiculares
/
Fertilização in vitro
/
Criopreservação
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Seminoma
/
Infertilidade Masculina
Tipo de estudo:
Clinical_trials
/
Etiology_studies
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article