A,D-seco-limonoids from the stems of Clausena emarginata.
J Nat Prod
; 77(4): 784-91, 2014 Apr 25.
Article
em En
| MEDLINE
| ID: mdl-24593150
ABSTRACT
Twelve new A,D-seco-limonoids, clauemargines A-L (1-12), and three known analogues were isolated from the stems of Clausena emarginata. The absolute configurations of 1 and 5 were confirmed by X-ray crystallography and ECD spectroscopy, respectively. Compounds 1, 2, 8-10, and 13 showed moderate inhibitory effects on LPS-induced NO production (IC50 values<10 µM).
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Medicamentos de Ervas Chinesas
/
Meliaceae
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Limoninas
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Clausena
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article