Focal bone lesions in HIV-positive patient treated with tenofovir.
BMC Infect Dis
; 14: 131, 2014 Mar 06.
Article
em En
| MEDLINE
| ID: mdl-24602357
ABSTRACT
BACKGROUND:
Tenofovir is a widely used antiviral drug for the treatment of HIV and HBV infection. Although its side effects on renal function and bone metabolism are well known, there are no reports on focal bone lesions caused by this drug. Our case suggests this new, unusual but important scenario. CASE PRESENTATION We report on a 46-year-old HIV-positive man treated with an antiretroviral regimen containing tenofovir who suddenly developed localized inflammatory bone lesions. The examinations performed ruled out all the disorders commonly associated with this clinical pattern, and the patient's conditions improved only after the suspension of tenofovir.CONCLUSIONS:
The case study suggests a rare but severe adverse event, which should be taken into account when physicians treat HIV-positive patients with focal inflammatory bone lesions.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças Ósseas
/
Adenina
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Infecções por HIV
/
Fármacos Anti-HIV
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Organofosfonatos
Limite:
Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article