Analysis of potential antiviral resistance mutation profiles within the HBV reverse transcriptase in untreated chronic hepatitis B patients using an ultra-deep pyrosequencing method.

Ciftci, Sevgi; Keskin, Fahriye; Cakiris, Aris; Akyuz, Filiz; Pinarbasi, Binnur; Abaci, Neslihan; Dincer, Erdinc; Badur, Selim; Kaymakoglu, Sabahattin; Ustek, Duran

Ciftci, Sevgi; Keskin, Fahriye; Cakiris, Aris; Akyuz, Filiz; Pinarbasi, Binnur; Abaci, Neslihan; Dincer, Erdinc; Badur, Selim; Kaymakoglu, Sabahattin; Ustek, Duran.

Afiliação

Ciftci S; Department of Microbiology, Faculty of Dentistry, Istanbul University, 34390 Istanbul, Turkey. Electronic address: sevgiciftci@gmail.com.
Keskin F; Department of Microbiology, Faculty of Dentistry, Istanbul University, 34390 Istanbul, Turkey.
Cakiris A; Institute for Experimental Medical Research, Istanbul University, 34393 Istanbul, Turkey.
Akyuz F; Department of Gastroenterohepatology, Faculty of Medicine, Istanbul University, 34093 Istanbul, Turkey.
Pinarbasi B; Department of Gastroenterohepatology, Faculty of Medicine, Istanbul University, 34093 Istanbul, Turkey.
Abaci N; Institute for Experimental Medical Research, Istanbul University, 34393 Istanbul, Turkey.
Dincer E; Institute for Experimental Medical Research, Istanbul University, 34393 Istanbul, Turkey.
Badur S; Microbiology and Clinical Microbiology, Faculty of Medicine, Istanbul University, 34093 Istanbul, Turkey.
Kaymakoglu S; Department of Gastroenterohepatology, Faculty of Medicine, Istanbul University, 34093 Istanbul, Turkey.
Ustek D; Institute for Experimental Medical Research, Istanbul University, 34393 Istanbul, Turkey.

Diagn Microbiol Infect Dis ; 79(1): 25-30, 2014 May.

Article em En | MEDLINE | ID: mdl-24630522

Assuntos

Antivirais/uso terapêutico; Vírus da Hepatite B/efeitos dos fármacos; Vírus da Hepatite B/genética; Hepatite B Crônica/virologia; Adolescente; Adulto; Farmacorresistência Viral/genética; Feminino; Genes Virais; Sequenciamento de Nucleotídeos em Larga Escala/métodos; Humanos; Masculino; Tipagem Molecular/métodos; Mutação; Análise de Sequência de DNA/métodos; Adulto Jovem

Palavras-chave

HBV-RT domain; Potential mutations; UDPS; Untreated chronic patients

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Vírus da Hepatite B / Hepatite B Crônica Limite: Adolescent / Adult / Female / Humans / Male Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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