The WIP1 oncogene promotes progression and invasion of aggressive medulloblastoma variants.

Buss, M C; Remke, M; Lee, J; Gandhi, K; Schniederjan, M J; Kool, M; Northcott, P A; Pfister, S M; Taylor, M D; Castellino, R C

Buss, M C; Remke, M; Lee, J; Gandhi, K; Schniederjan, M J; Kool, M; Northcott, P A; Pfister, S M; Taylor, M D; Castellino, R C.

Afiliação

Buss MC; Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA, USA.
Remke M; Division of Neurosurgery, Arthur and Sonia Labatt Brain Tumour Research Center, Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Lee J; Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA, USA.
Gandhi K; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA.
Schniederjan MJ; Department of Pathology, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA, USA.
Kool M; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Northcott PA; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Pfister SM; 1] Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany [2] Department of Pediatric Hematology, Oncology and Immunology, Heidelberg University Hospital, Heidelberg, Germany.
Taylor MD; Division of Neurosurgery, Arthur and Sonia Labatt Brain Tumour Research Center, Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Castellino RC; Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA, USA.

Oncogene ; 34(9): 1126-40, 2015 Feb 26.

Article em En | MEDLINE | ID: mdl-24632620

Assuntos

Neoplasias Cerebelares/patologia; Quimiocina CXCL2/metabolismo; Quinase 5 de Receptor Acoplado a Proteína G/metabolismo; Meduloblastoma/patologia; Fosfoproteínas Fosfatases/genética; Receptores CXCR4/genética; Adolescente; Animais; Linhagem Celular Tumoral; Neoplasias Cerebelares/genética; Criança; Pré-Escolar; Feminino; Quinase 5 de Receptor Acoplado a Proteína G/genética; Humanos; Lactente; Masculino; Meduloblastoma/genética; Camundongos; Camundongos SCID; Invasividade Neoplásica; Transplante de Neoplasias; Fosfoproteínas Fosfatases/metabolismo; Proteína Fosfatase 2C; Receptores CXCR4/metabolismo; Transdução de Sinais; Adulto Jovem

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Cerebelares / Fosfoproteínas Fosfatases / Receptores CXCR4 / Quinase 5 de Receptor Acoplado a Proteína G / Quimiocina CXCL2 / Meduloblastoma Limite: Adolescent / Adult / Animals / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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