Production of anti-HBsAg monoclonal antibodies.
Braz J Med Biol Res
; 21(3): 507-9, 1988.
Article
em En
| MEDLINE
| ID: mdl-2465803
ABSTRACT
The production of monoclonal antibodies against the HBsAg is reported. Balb/c mice immunized against a commercial vaccine were used. Upon fusion of spleen cells from an animal having a high titer with the SP2/0 myeloma cell line, we obtained 6 stable cell lines, all of the IgG1 subclass. They showed a wide range of specificities against the classical HBsAg subtypes. These monoclonal antibodies can be used as the basis for the development of new methods for the screening and study of the hepatitis B virus.
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Base de dados:
MEDLINE
Assunto principal:
Anticorpos Anti-Hepatite B
/
Antígenos de Superfície da Hepatite B
/
Anticorpos Monoclonais
Limite:
Animals
Idioma:
En
Ano de publicação:
1988
Tipo de documento:
Article