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ST2 deficiency does not impair type 2 immune responses during chronic filarial infection but leads to an increased microfilaremia due to an impaired splenic microfilarial clearance.
Ajendra, Jesuthas; Specht, Sabine; Neumann, Anna-Lena; Gondorf, Fabian; Schmidt, David; Gentil, Katrin; Hoffmann, Wolfgang H; Taylor, Mark J; Hoerauf, Achim; Hübner, Marc P.
Afiliação
  • Ajendra J; Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany.
  • Specht S; Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany.
  • Neumann AL; Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany.
  • Gondorf F; Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany.
  • Schmidt D; Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany.
  • Gentil K; Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany.
  • Hoffmann WH; Institute of Tropical Medicine, University of Tuebingen, Tuebingen, Germany.
  • Taylor MJ; Filariasis Research Laboratory, Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
  • Hoerauf A; Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany.
  • Hübner MP; Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany.
PLoS One ; 9(3): e93072, 2014.
Article em En | MEDLINE | ID: mdl-24663956
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Baço / Receptores de Interleucina / Filariose / Filarioidea Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Baço / Receptores de Interleucina / Filariose / Filarioidea Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article