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Sirukumab, a human anti-interleukin-6 monoclonal antibody: a randomised, 2-part (proof-of-concept and dose-finding), phase II study in patients with active rheumatoid arthritis despite methotrexate therapy.
Smolen, Josef S; Weinblatt, Michael E; Sheng, Shihong; Zhuang, Yanli; Hsu, Benjamin.
Afiliação
  • Smolen JS; Division of Rheumatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria Department of Medicine, Hietzing Hospital, Vienna, Austria.
  • Weinblatt ME; Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Sheng S; Janssen Research & Development, LLC, Quantitative Sciences, Spring House, Pennsylvania, USA.
  • Zhuang Y; Janssen Research & Development, LLC, Biologics Clinical Pharmacology, Spring House, Pennsylvania, USA.
  • Hsu B; Janssen Research & Development, LLC, Immunology, Spring House, Pennsylvania, USA.
Ann Rheum Dis ; 73(9): 1616-25, 2014 Sep.
Article em En | MEDLINE | ID: mdl-24699939
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Interleucina-6 / Antirreumáticos / Anticorpos Monoclonais Tipo de estudo: Clinical_trials / Diagnostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Interleucina-6 / Antirreumáticos / Anticorpos Monoclonais Tipo de estudo: Clinical_trials / Diagnostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article