Infective endocarditis after renal transplantation.
Nephrourol Mon
; 6(1): e12326, 2014 Jan.
Article
em En
| MEDLINE
| ID: mdl-24719812
ABSTRACT
BACKGROUND:
Infective endocarditis (IE) is a serious complication in immunosuppressive patients that has adverse effects.OBJECTIVES:
The aim of this study was to define the characteristics, outcomes, and correlating factors of mortality in renal transplant recipients. PATIENTS ANDMETHODS:
Infective endocarditis was diagnosed in 22 patients from three renal transplant centers in Iran between 2000 and 2010. Modified Duke criteria were applied to confirm the diagnosis.RESULTS:
Twenty-two renal transplant patients with IE were evaluated. Blood culture results were positive in 81%. Enteroccous and group D non-enterococcal were the causative microorganisms in 31% and 25% of patients, respectively. In-hospital and 12-month mortality was 41% and the mortality rate was higher in older patients in comparison to younger patients. Overall, the rates of one-year disease-free patient and graft survival were 49% and 88%, respectively.CONCLUSIONS:
Despite the availability of different and potent antibiotics, the mortality caused by IE remains considerably high. These patients are significantly prone to endovascular infections that affect the mortality and survival.
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Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article