Risk factors for adult-onset recurrent respiratory papillomatosis.
Laryngoscope
; 124(10): 2338-44, 2014 Oct.
Article
em En
| MEDLINE
| ID: mdl-24764146
ABSTRACT
OBJECTIVES/HYPOTHESIS:
To evaluate risk factors strongly associated with adult-onset recurrent respiratory papillomatosis (AO-RRP). STUDYDESIGN:
Prospective, age- and sex-matched, case control.METHODS:
Patients with AO-RRP and controls completed a computer-based, 89-item questionnaire across three academic institutions.RESULTS:
Forty-eight AO-RRP patients were compared to 73 controls; 43 of the 48 AO-RRP patients were male (89.5%). The difference in the median number of lifetime sexual partners between AO-RRP (15) and controls (10) was significant (P = 0.0387). Additionally, an increased number of lifetime sexual partners (≥ 26) was associated with AO-RRP. No significant difference for the number of lifetime oral sex partners was observed between groups. Increased comorbidity, as quantified by the Charlson Comorbidity Index, was observed in patients with AO-RRP. AO-RRP and control groups were similar across many other variables, including birth history, smoking history, alcohol use, drug use, education, income, and the Short Form Health Survey scores.CONCLUSIONS:
AO-RRP was not associated with previously proposed risk factors for juvenile-onset RRP and may be associated with an increased number of lifetime sexual partners.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infecções Respiratórias
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Doenças Virais Sexualmente Transmissíveis
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Medição de Risco
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Infecções por Papillomavirus
Tipo de estudo:
Clinical_trials
/
Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
/
Middle aged
País como assunto:
America do norte
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article